Release date: 2007-08-07
New glaucoma therapy developed in the United States A research team at Iowa State University found that glaucoma can be effectively treated by transplanting specially modified bone marrow stem cells. Next, the researchers plan to conduct new therapy experiments on dogs. From a physiological point of view, the dog's eyes and the human eye have a high degree of similarity, which can provide an important basis for human clinical trials.
Researchers believe that this new treatment is expected to be used in human patients in the future.
The team has previously found that glaucoma-producing animals produce more neurotrophins to protect themselves from blindness. Therefore, they simulated the self-defense mechanism of animals in the laboratory. First, the bone marrow stem cells were extracted from the glaucoma-bearing mice themselves, and the culture was improved to generate neurotrophins, and then the modified cells were injected into the eyes of the affected mice. It was found that the visual function of the diseased mice was significantly improved.
The benefit of the new treatment is that the transplanted cells can produce opioid nutrients for several years, and the bone marrow stem cells can be obtained from the patient's own body, avoiding rejection.
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