Clinical application of trichosanthin

Clinical application

1, for induction of labor: the induction of mid-pregnancy, stillbirth, expired abortion has a high efficacy, simple method, less bleeding and so on.

Preparation and usage:

An injectable trichosanthin: Before the injection, the trichosanthin was diluted with normal saline to a concentration of 2 micrograms per milliliter, 0.05 milliliter was injected into the forearm flexor skin, and the skin test result was observed after 20 minutes. If it was negative, deep intramuscular injection was possible. 0.2 mg trichosanthin powder was used as a trial test. If no reaction was observed within 2 hours, deep muscle injection of 5-8 mg was possible. According to 2000 cases of mid-term pregnancy, stillbirth, overdue abortion induction observation; success rate of about 95%, of which the effect of stillbirth induced labor is more prominent.

Take two days of trichosanthin powder, 0.5 grams of pig tooth soap powder, add water into a paste, gauze bandage, into the vagina after the fistula, after 24 hours can force mid-pregnancy, stillbirth, expired abortion, grape-like lumps and other natural discharge. General bleeding is not much, little pain, after a smooth. Application of 147 cases, the success rate of 93.2%.

Three to take 70 to 80 mg of anthocyanin, 40 mg of saponin and mix it into capsules. Take 1 capsule into the vagina after use. After 12 to 24 hours, side effects such as chills, fever, and joint pain usually occur for about 2 days. The body temperature, pulse, and blood pressure are measured at 4 hours after the drug is taken. If the body temperature exceeds 38.5°C or the blood pressure is lower than 90/60 mm Hg, desensitization and symptomatic treatment shall be performed immediately to avoid accidents. Drink more water during treatment. Usually within 3 to 6 days can be delivered naturally. Observed 1046 cases; 1 successful 973 cases, the success rate was 93%. However, the side effects of the two or three methods are serious and are rarely used.

2, with the trichosanthin protein 5g, intramuscular injection, treatment of hydatidiform mole 129 cases, natural excretion in 55 cases, accounting for 42.6% (Yunnan Medicine, 1978, 3:1);

3, with Tian soap mixture, vaginal plug medicine, treatment of 7 cases of malignant trophoblastic tumors, including malignant hydatidiform mole in 5 cases were cured, 2 cases of villous cancer was invalid (Jiangsu Pharmaceutical, 1978, 6:5);

4, in addition, clinical use of TCS for the treatment of diabetes, acute bronchitis, pneumonia, mastitis, mumps and other infectious diseases and for the induction of labor in mid-pregnancy, anti-pregnancy, expired miscarriage stillbirth, ectopic pregnancy, intestinal metaplasia and so on.


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