Also known as: jujube. Prescription name: Hawthorn, Hawthorn meat. 
ã€Sexual taste and efficacy】
It is sour, sputum and mild. Efficacy: nourishing liver and nourishing blood, kidney and phlegm.
[traditional application]
Indications of liver and kidney deficiency, dizziness, backache, tinnitus; nocturnal emission, enuresis, frequency of urination.
This medicine is often used in the following traditional prescriptions: Shan Lai Pills ("Puji Fang"): Hawthorn, Raspberry, Dodder, Basil, Ginseng, Poria, Schisandra, Rehmannia, Gui, Tianxiong, Caotun, Cattle Knee, treatment of kidney deficiency, waist and knee weakness, frequent urination.
This product is available in Liuwei Dihuang Pill and its flavoring formula.
[main ingredients]
It mainly contains glycosides of glucosides, organic acids and tannins.
1. Glycosides: Hawthorn glycosides (ie, verbena), iridoid glycosides.
2. Organic acids: ursolic acid, gallic acid, malic acid, tartaric acid.
3. Fatty oil: palmitic acid, oleic acid, linoleic acid, and the like.
4. Other vitamin A, saponin, citric acid, etc.
[Pharmacological action]
(1) Blood supplement The mice can drink Hawthorn decoction for 60 days, which can significantly increase the content of hemoglobin.
This product decoction has an increasing effect on leukopenia caused by chemotherapy and radiotherapy.
(B) strong heart and boost Shanshan injection can enhance myocardial contractility, improve heart efficiency, expand peripheral blood vessels, significantly enhance the heart pumping function, can raise blood pressure, and has anti-shock effect.
(III) Effects on immune function Hawthorn has both inhibitory and immune components.
1. Immunosuppression: Hawthorn glycosides have immunosuppressive effects, which can significantly inhibit lymphocyte transformation and inhibit the production of interleukin-2 (1L-2).
Hawthorn glycosides can significantly inhibit the rejection of transplanted hearts and significantly prolong the survival time of transplanted hearts in mice. The total glycosides of hawthorn have a synergistic effect with cyclosporin A.
2. Immunization enhancement: High doses of hawthorn can enhance the phagocytic function of macrophages and increase the weight of spleen.
This product has an enhanced effect on humoral immune function, which can increase the content of hemolysin antibody in mice and increase the serum antibody IgG content.
3. Immunomodulation: Hawthorn strychnin has a two-way effect on the immune response. In vitro experiments, lymphocyte transformation, inhibition at high concentrations, promotion at low concentrations. The in vivo administration of the scorpion scorpion can significantly increase the ability of mouse lymphocytes to produce IL-2.
4. Anti-allergic reaction: It has anti-allergic and anti-allergic effects, can significantly inhibit the delayed swelling of mice caused by SRBC, significantly reduce the contact dermatitis caused by DNCB (dinitrochlorobenzene), increase the dose After the mouse contact dermatitis has a significant inhibitory effect.
(4) Anti-inflammatory product Decoction can inhibit the increase of peritoneal capillary permeability caused by acetic acid, rat granulation tissue hyperplasia, swelling of auricle caused by F0 benzene, and swelling of rat's ankle caused by egg white , reduce the content of ascorbic acid in the adrenal gland. Its anti-inflammatory mechanism may be related to the function of the pituitary-adrenal system.
(5) Lipid-lowering and hypoglycemic and inhibition of platelet aggregation The 20g/kg mice of the scorpion alcohol extract were intragastrically administered for 7 consecutive days, which significantly reduced the blood sugar, serum total cholesterol and triglyceride content of normal mice.
The extract of Cornus officinalis has a significant inhibitory effect on ADP-induced platelet aggregation in vitro and a decrease in the viscosity of whole blood in rabbits. It has a certain antagonistic effect on pulmonary embolism induced by platelet aggregation, and the duration of respiratory asthma in mice is significantly shorter than that of the control group.
(6) Others 1. Enhance physical strength and anti-hypoxia effect: After 60 days of drinking water in mice, the swimming time and anti-hypoxia ability were significantly improved.
2. Puzzle: After 60 days of drinking in the decoction of the product, the time required for the labyrinth foraging experiment was significantly shorter than that of the control group.
3. Others: This product is also beneficial to the urine, antibacterial effect, and weaker excitatory parasympathetic nerves.
ã€Clinical application】
1. Treatment of physical weakness, dizziness, weakness, waist and knees, impotence and nocturnal emission, urinary frequency and urgency, and other symptoms of liver and kidney deficiency.
2. Treatment of anemia and leukopenia caused by chemotherapy and radiotherapy.
[Dose and usage]
Pharmacopoeia dose: 6 ~ 12g.
Clinically used dose: 6 ~ 12g.
Large dose: generally not used in large doses.
Usage: Shuijianbi;
[Clinical experience]
(A) on the benefits of replenishing 1. Liver and kidney: Hawthorn meat is the first to supplement the liver and kidney medicine, in the Liuwei Dihuang Pills in combination with Dihuang as a drug to replenish liver and kidney. Frequent symptoms of the elderly, such as dizziness, weakness, waist and knees, impotence and nocturnal emission, urinary frequency and urgency, etc. - are a sub-health state, not necessarily organic disease, syndrome differentiation is liver and kidney deficiency. In this case, hawthorn meat is a commonly used traditional Chinese medicine. Long-term use can enhance physical fitness, strong heart, anti-fatigue, and immune function.
Because the hawthorn meat has the effect of lowering blood sugar and lowering sugar and anti-poly-anti-thrombosis, it is very beneficial for the elderly to take it for a long time.
2. About blood and whitening: Hawthorn meat has the effect of raising hemoglobin and white blood cells. Traditional Chinese medicine theory, liver blood, kidney essence, hemoglobin reduction and leukopenia belong to liver blood deficiency, blood does not raise liver. For the treatment, Liuwei Dihuang Pills and Erzhi Pills, such as Dihuang, Ligustrum lucidum, and Hawthorn meat, are used to nourish liver and tonify liver and blood. Hemoglobin and leukopenia caused by various factors, such as nutritional, hyperplastic, chemotherapy and radiotherapy, can be used.
3. Regarding the regulation of immune function: Hawthorn meat pharmacology reports both the side that suppresses immunity and the side that enhances immunity. Our clinical use of hawthorn meat is often used to replenish liver and kidney and blood. The conventional dose is not very large, so the effect on immune function has not been reflected. Pharmacologically suggest that Hawthorn saponins have anti-rejection effects, and because of the few drugs in this area, they can be used in clinical practice.
(2) About Gushu Mountain meat is a solid astringent medicine. It has a rich acidity and contains more organic acids and tannic acid. Organic acids and tannins are common ingredients in many traditional Chinese medicines, but only a few Chinese medicines contain a large amount of organic acids and tannins. These ingredients reach a certain level, making Chinese medicines mainly based on acidity. Most of these drugs are classified in the drug.
The pharmacological action of citric acid has antibacterial and astringent effects. Hawthorn meat does have clinical effects in this regard.
1. The antibacterial effect of antibacterial hawthorn meat is related to tannic acid, mainly inhibiting Escherichia coli and dysentery bacilli, and can be used for chronic urinary tract infection, chronic prostatitis, urinary leaching, chronic intestinal infection and ulcer, stool The second time is thin or sometimes with pus and blood, and the syndrome is a patient with two losses of spleen and kidney.
2. The astringent effect of astringent hawthorn meat, including urinating, concentrating, concentrating, concentrating, and sweating. Clinical diagnosis of chronic urinary tract infection and post-infection urinary tract syndrome, nocturnal emission and premature ejaculation, chronic cervicitis, excessive vaginal discharge, chronic intestinal infection, thin stools, autonomic dysfunction and sweat. Hawthorn meat is clinically effective for these five chronic diseases that need to converge. For sweating, the use of hawthorn meat is slightly weaker and should be used in combination.
3. Tannic acid also has a hemostatic effect. However, in addition to solidification and hemostasis, hawthorn meat is generally not used to treat bleeding in other parts.
4. For patients with chronic bowel movements, but patients with poor bowel movements, abdominal distension, and urgency, it is not advisable to use yam meat.
ã€side effect】
(1) Traditional literature "Compendium of Materia Medica": non-toxic.
(2) Toxicological test Toxic reaction: Hawthorn fluid has no effect on body weight, blood and conjunctiva of frogs, rats and rabbits, and can cause congestion of gastric mucosa in rabbits. Hawthorn glycosides are very low in toxicity, do not hemolyze, and have weaker effects of parasympathetic nerves.
(C) Clinical observation Hawthorn meat is non-toxic. Shuijianbi has no side effects in regular doses. There are no obvious side effects when taken for a long time. It is not convenient to use it.
The main technical parameters of Hawthorn decocting machine :
Production capacity: 5-8fu/h
Bagload: 210ml
Voltage: 220V
Power: 2440W
Weight: 80kg
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