High Purity Topiramate Powder for Anticonvulsant CAS 97240-79-4

Topiramate Product Name: Topiramate
Topiramate CAS: 97240-79-4
Topiramate MF: C12H21NO8S
Topiramate MW: 339.36
Topiramate EINECS: 200-659-6
Topiramate Product Categories: Active Pharmaceutical Ingredients;APIs;Health & Beauty;Carbohydrates & Derivatives;Pharmaceuticals;Glutamate receptor;Intermediates & Fine Chemicals;API;TOPAMAX;Pharmaceutical raw materials
Topiramate Melting point : 125°C
Topiramate Storage temp. : 2-8°C
Topiramate Chemical Properties : White-to-Off-White Crystalline Powder
Topiramate Usage : anticonvulsant, antimigraine, GABA-A agonist, AMP/kinate glutamate receptor antagonist, carbonic anhydrase inhibitor

Topiramate is used to treat epilepsy in children and adults, and it was originally used as an anticonvulsant.In children, it is indicated for the treatment of Lennox-Gastaut syndrome, a disorder that causes seizures and developmental delay. It is also Food and Drug Administration (FDA) approved for, and most frequently prescribed for, the prevention of migraines. The drug is also used to treat migraines due to the effect it has on the blood vessels in the brain. It has been found to be increasingly effective for migraine sufferers with limited side effects.

Pharmacological Effects

The major mechanism of Topiramate is through blocking the dispersion of epileptic seizures rather than preventing its occurrence. It has been also found that TPM can exert its efficacy in treating epilepsy through various kinds of mechanisms including:

1, blocking the voltage-dependent sodium channels and thereby reducing the duration of epileptic discharges and the number of action potentials generated during each discharge.

2, antagonizing kainate/AMPA--glutamate receptors.

3, enhancing the GABA activity in the non-benzodiazepine position of the GABA receptor.

4, mildly inhibiting carbonic anhydrase.

5, blocking the T-type calcium channels.

6, block the activity of the excitatory neurotransmitter of the central nervous AMPA glutamate receptor.

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  Topiramate Product Name: Topiramate
Topiramate CAS: 97240-79-4
Topiramate MF: C12H21NO8S
Topiramate MW: 339.36
Topiramate EINECS: 200-659-6
Topiramate Product Categories: Active Pharmaceutical Ingredients;APIs;Health & Beauty;Carbohydrates & Derivatives;Pharmaceuticals;Glutamate receptor;Intermediates & Fine Chemicals;API;TOPAMAX;Pharmaceutical raw materials
Topiramate Melting point : 125°C
Topiramate Storage temp. : 2-8°C
Topiramate Chemical Properties : White-to-Off-White Crystalline Powder
Topiramate Usage : anticonvulsant, antimigraine, GABA-A agonist, AMP/kinate glutamate receptor antagonist, carbonic anhydrase inhibitor

Topiramate is used to treat epilepsy in children and adults, and it was originally used as an anticonvulsant.In children, it is indicated for the treatment of Lennox-Gastaut syndrome, a disorder that causes seizures and developmental delay. It is also Food and Drug Administration (FDA) approved for, and most frequently prescribed for, the prevention of migraines. The drug is also used to treat migraines due to the effect it has on the blood vessels in the brain. It has been found to be increasingly effective for migraine sufferers with limited side effects.

Pharmacological Effects

The major mechanism of Topiramate is through blocking the dispersion of epileptic seizures rather than preventing its occurrence. It has been also found that TPM can exert its efficacy in treating epilepsy through various kinds of mechanisms including:

1, blocking the voltage-dependent sodium channels and thereby reducing the duration of epileptic discharges and the number of action potentials generated during each discharge.

2, antagonizing kainate/AMPA--glutamate receptors.

3, enhancing the GABA activity in the non-benzodiazepine position of the GABA receptor.

4, mildly inhibiting carbonic anhydrase.

5, blocking the T-type calcium channels.

6, block the activity of the excitatory neurotransmitter of the central nervous AMPA glutamate receptor.

Related product list
 
Our Advantage



 

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