[ China Pharmaceutical Network Technology News ] Cancer cells are a kind of mutated cells, which are the source of cancer. Different from normal cells, cancer cells have three characteristics of unlimited proliferation, transformation and easy transfer, which can proliferate and destroy normal cells infinitely. Organization, it is difficult to eliminate. It is reported that space can effectively cultivate the structure of 3D cancer cells closer to the structure of cancer cells in human body. With a biological printing method called "magnetic 3D cell culture", researchers can better study cancer cells.
It is reported that NASA's affiliated research center BioServe Space Technologies is carrying out a research project called "Magnetic 3D Cell Culture". The project uses a bioprinting technology developed on Earth to train more realistic cancer cells on the International Space Station (ISS) to advance cancer treatment research.
In humans, the structure of cancer cells is very complex and almost spherical, while cancer cells cultured in the laboratory (in vitro) have only a layered structure. Researchers at the center believe that in space, they can effectively culture 3D cancer cell structures that are closer to the structure of cancer cells in the human body. Using a bioprinting method called "magnetic 3D cell culture", the researchers found that the microgravity environment on the ISS could be used by them.
By printing gold atoms into a polymer matrix on human cancer cell cultures (they used lung cancer cells in the experiment), researchers can use magnets to control cell structure and movement. This is because the gold atoms strongly bind to the cell membrane, making them magnetically reactive.
"This technology may allow us to process cells in the sky in a way that is currently impossible. On Earth, you put cells in a biofilm medium and cells grow on their surface. But this is in space. It won't happen because there isn't enough gravity to keep them on the surface. So now we will use a medium to culture the cells on the ground, then launch them into space and start the experiment. Use these magnets. Particles, we can start culturing cells in space, just like on Earth," the researchers explained.
It has been reported that the addition of gold atoms to cancer cells for operational purposes does not interfere with or affect the biological processes of the cells, and thus the use of this bioprinting technique for cancer research is feasible. In addition, cultivating cancer cells with more realistic structures may reduce the cost of drug development and may bring other benefits. “This survey tested a new technology that other scientists can apply to their research as appropriate,†the researchers concluded.
(Cultivating real cancer cells 3D bioprinting advances cancer treatment)
It is reported that NASA's affiliated research center BioServe Space Technologies is carrying out a research project called "Magnetic 3D Cell Culture". The project uses a bioprinting technology developed on Earth to train more realistic cancer cells on the International Space Station (ISS) to advance cancer treatment research.
In humans, the structure of cancer cells is very complex and almost spherical, while cancer cells cultured in the laboratory (in vitro) have only a layered structure. Researchers at the center believe that in space, they can effectively culture 3D cancer cell structures that are closer to the structure of cancer cells in the human body. Using a bioprinting method called "magnetic 3D cell culture", the researchers found that the microgravity environment on the ISS could be used by them.
By printing gold atoms into a polymer matrix on human cancer cell cultures (they used lung cancer cells in the experiment), researchers can use magnets to control cell structure and movement. This is because the gold atoms strongly bind to the cell membrane, making them magnetically reactive.
"This technology may allow us to process cells in the sky in a way that is currently impossible. On Earth, you put cells in a biofilm medium and cells grow on their surface. But this is in space. It won't happen because there isn't enough gravity to keep them on the surface. So now we will use a medium to culture the cells on the ground, then launch them into space and start the experiment. Use these magnets. Particles, we can start culturing cells in space, just like on Earth," the researchers explained.
It has been reported that the addition of gold atoms to cancer cells for operational purposes does not interfere with or affect the biological processes of the cells, and thus the use of this bioprinting technique for cancer research is feasible. In addition, cultivating cancer cells with more realistic structures may reduce the cost of drug development and may bring other benefits. “This survey tested a new technology that other scientists can apply to their research as appropriate,†the researchers concluded.
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